Comparison of depressive episodes in bipolar disorder and in major depressive disorder within bipolar disorder pedigrees

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Comparison of depressive episodes in bipolar disorder and in major depressive disorder within bipolar disorder pedigrees.

BACKGROUND Although genetic epidemiological studies have confirmed increased rates of major depressive disorder among the relatives of people with bipolar affective disorder, no report has compared the clinical characteristics of depression between these two groups. AIMS To compare clinical features of depressive episodes across participants with major depressive disorder and bipolar disorder...

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OBJECTIVE Some studies suggest that depressive subtypes, defined by groups of symptoms, have predictive or diagnostic utility. These studies make the implicit assumption of stability of symptoms across episodes in mood disorders, which has rarely been investigated. METHODS We examined prospective data from a cohort of 3,750 individuals with bipolar I or II disorder participating in the System...

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 2011

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.bp.110.088823